Thứ Sáu, 15 tháng 2, 2019

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At McLaren we see our fans as an extension of our team.

So here we are the night before our MCL34 car launch, we gathered a group of our most

loyal fans and we're going to show it to those guys first.

You guys are having your own private car launch. Upstairs. Now.

Give me a break!

Amazing, amazing.

Words can't describe it man.

So, I've seen the greatest walkway, that leads to the most beautiful little bar.

They took us to an awesome little cinema, where we watched a brilliant little film that

just encompassed everything McLaren is.

Then they announced we were going to see the car, the car before anyone else sees it.

See you guys!

Usually there are no words to experience something like this, and family and the stuff that this brings.

McLaren, you do mean everything to us, and that's why we support you the way we do.

Thank you, thank you, thank you.

Absolutely amazing to see the new car, just fresh out from seeing it.

It looks like a lot of hard work and detail has certainly gone into it, gave me goosebumps

seeing it.

I've just seen the car, it looks absolutely incredible.

I can tell that there's been masses of work that's gone into it and for it to be revealed

by the two drivers was a really special moment I will never forget, and that car is always

going to be special because we were lucky enough to see it first.

It was incredible.

For more infomation >> A night to remember - Duration: 3:05.

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The Strategy of Eurasianism - Duration: 26:08.

This video will be about the strategy of Eurasianism, a set of cultural, philosophical and political

concepts centered on the idea that Eurasia – defined as the former Soviet space minus

the Baltics and plus Mongolia and sometimes northwest China – has an independent civilizational

identity and developmental path.

In particular, we will answer the following questions:

- How does Eurasianism define power?

- What is the global distribution of power?

- And how can power be organized and manipulated to achieve Eurasianism's goals?

To be honest, there isn't actually a 'standard' form of Eurasianism that reconciles all its

major strands of thought.

No 'State Eurasianism' has ever existed to translate theory into actual policy.

So while most Eurasianists share the video's strategic logic, the precise details, emphasis

and policies will inevitably vary.

Nevertheless, we can group Eurasianist theory into three subsets.

The first is 1920s Classical Eurasianism, including the post-Revolution exiles Petr

Savitsky and Nikolai Trubetzkoy.

Viewing Czarist Westernization as the root cause of Russia's collapse, and wary of

the challenge that post-WWI 'self-determination' posed to its integrity, Classical Eurasianism

focuses on establishing Russia's geographical and philosophical separation from the West.

Eurasianism during the Soviet period pretty much consisted solely of the work of Lev Gumilev,

whose work on history and ethnography underlay a desire to reject what he saw as a Western-oriented

view of Russian history in favor of linking Russia with the peoples of Central Asia.

Lastly, Neo-Eurasianism was a response to disillusionment with the results of Soviet

collapse.

Rejecting the idea that Russia's rejuvenation lies in the West, political and geopolitical

thinkers such as Aleksandr Panarin and Aleksandr Dugin seek to carve out new ideological and

political niches where Russia could reestablish its relevance.

Eurasianism focuses on four levels of analysis: the state; the 'people' or ethnos to use

the Gumilevian term; the 'culture group' or superethnos; and the 'civilization'.

'People' and 'culture group' are groupings based on shared behavior; and the 'civilization'

encompasses them all through a set of shared values and what is referred to as 'common

historical destiny'.

Day-to-day political power rests with the state, but this is underwritten by the civilizational

values of the peoples and culture groups it governs: should their values change, the state

loses legitimacy and collapses.

Therefore, organizing and maintaining ideological power in the form of civilizational values

is a key, if not the key aspect of Eurasianist strategy.

For Eurasianism, geography determines the global distribution of power, but not in the

sense of resource distribution.

Instead, geography shapes the existence, size, and compatibility of peoples, culture groups

and civilizations.

Gumilev's theory of ethnogenesis states that humanity adapts to local environments

by changing behavior and values.

Each people, culture and civilization therefore corresponds to a specific mestorazvitie or

'place of development', and their values represent a specialized and unique adaptation

to Earth's geography.

Civilizational-level mestorazvities generally consist of continental-sized ecological blocs:

Europe's wooded peninsulas for the Western European civilization, the desert plains of

the Arabian Desert for the Arab Muslim civilization, and so on.

But in Europe and Asia's northern reaches, Classical Eurasianists claimed the existence

of not simply a bloc, but a complete geographic system.

Here, regional bands of tundra, taiga, steppe and desert span nearly half the globe in a

regular progression, hosting the culture groups of the Uralics, Russians, Northern Turkics

and Southern Turkics respectively.

These bands are bound together thanks to three 'zones of interaction': the Russian plain,

the Turkestani plain, and the West Siberian plain.

Acting as regions of ecological and intercultural exchange, these plains eventually induced

what Gumilyov called komplimentarnost or mutual trust between the culture groups, from which

emerged a unified 'Eurasian civilization'.

But if plains create komplimentarnost between Eurasians, then perhaps similar trust would

be created with the Western Europeans as well?

This possibility was strongly denied by the Classical Eurasianists, who came up with a

host of differences – temperature differentials, linguistic phonology, agricultural practice

– to assert a geographic and civilizational separation between Eurasia and Western Europe.

So from geography, Eurasianists derive several points: Eurasia exists naturally as an independent

system, meaning that the Eurasian civilization it birthed possesses its own unique values.

These values represent a unique adaptation to their environment, as do the values of

other civilizations.

Ideological differences are therefore a reflection of Earth's diversity, and any talk of 'universal

values' is largely meaningless.

In an ideal Eurasianist world, every civilization would thus leave each other alone to develop

in its own way.

But alas, there is one civilization that will not do that.

Classical Eurasianists identified it as the 'Romano-Germanic' civilization of Western

Europe, while for the Neo-Eurasianists it is the 'Atlantic' civilization of the

Anglophone states.

The key feature of their mestorazvities is a peninsular or islandic geography, whose

sea-based or thalassocratic nature encouraged commerce and trade.

These in turn produced civilizational values of individual competition, materialism and

standardization, underlying modern-day Western liberal, rationalist, and universalist ideology.

Eurasianists have no problem with Western values within their own civilization.

But universalism by definition has larger ambitions, so the West insists on exporting

its values globally.

This insistence comes in two ways: first, a quest to convert others to Western values;

and second, the creation of a values discourse that judges civilizations as 'progressive'

or 'backward' depending on how closely they match Western society.

Furthermore, universalism goes hand-in-hand with Western global hegemony, exemplified

in the colonial empires, American unipolarity and global capitalism.

It does this in two ways: firstly, by encouraging other civilizations to waste energy unlearning

their own values, and becoming imitators always one step behind the actual Westerners.

Secondly, since Atlantic values come from a distinct environment, adopting them in a

different geographic context disassociates civilizations from their own environment,

creating internal splits that allow Westerners to divide and conquer.

In such a way, Classical Eurasianists argued that Czarist Westernization created schisms

between the aristocracy and the masses, and between the Russians and the other peoples,

which with the victory of Western-originated revolutionary Marxism finally tore the civilization

apart in class and ethnic war.

The Neo-Eurasianist Dugin saw similar results coming out of de-Stalinization, perestroika

and Yeltsin-era shock therapy.

Eurasianists see the logical conclusion of all this as the global dominance of a Western

oligarchy that enriches itself by exploiting a subjugated and chaotic world.

There is therefore not just a Russian, but also a global imperative to resist Western

universalism.

Unsurprisingly, Eurasianism sees Eurasia as the natural leader of the anti-Western resistance.

Taking a page from Mackinder's Heartland Theory, Eurasianists argue that Eurasia's

geographic nature as a self-contained, inner continental 'tellurocracy' makes it far

less vulnerable to Western sea-based 'thalassocratic' pressure compared with other coastal civilizations.

Only a unified Eurasia can assist other civilizations without worrying about its own back.

So how can Eurasia's unification be brought about?

First, we need to define 'unification', which to Eurasianism isn't necessarily complete

political unification.

Because each people represents a specialized adaptation to its environment, local autonomy

should be protected, with unity needed only on issues of civilizational importance, such

as foreign policy, inter-group relations, macroeconomics and a common ideological infrastructure.

It's possible that Eurasianists would be satisfied with a bloc of Russia-aligned states

that are generally sovereign but reliably defer to Moscow in select areas.

Secondly, Eurasianism places great stock in the idea that political arrangements trend

towards a 'natural order', most of all the idea that geographical unity naturally

leads to political unity.

The fact that it doesn't in reality is therefore the result of nature-violating 'artificial

forces', i.e.

Western material power, or the spread of Western values such as 'self-determination'.

Drawing on these ideas, Eurasianists recommend Russia – always the unifying state thanks

to its size and extensive interaction with all other Eurasian peoples – pursue policies

that defend or cordon off Eurasian states against Western power, allowing nature to

take its course.

Dugin proposes a neutral bulwark stretching across Eastern Europe and the Middle East:

not only does this physically separate Eurasia from Western power, it also shifts the focus

of Western energies away from Eurasia proper.

Ideologically, even without total communications control, cordoning-off could take the form

of alternative media and facts or outright disinformation and conspiratology.

Eurasian unification also requires proper internal organization.

To defend the unity against future Western universalist attempts, the Classical Eurasianists

in particular called for ideological conformity and mobilization under what they called an

'ideocracy'.

Here Classical Eurasianists saw the policies of Fascist Italy as a potential model, while

Dugin looks to Stalinism.

The exact content of Eurasian ideology is significantly more debated.

Most Eurasianists agree on two concepts: first, rejecting Western values discourse on universal

rights, individualism, materialism, and 'progress', and instead promoting 'natural values'

of collectivism, spirituality, and civilizational uniqueness.

Second, reinforcing komplimentarnost between the Eurasian peoples.

Gumilev, in particular, rejected what he saw as the 'Black Legend' of the Mongol and

Tatar Yoke on medieval Rus, seeing it as Western exaggeration to sow division between the Russians

and the Central Asians.

There is significant disagreement on how 'Russian' Eurasianist ideology should be.

Classical Eurasianists insisted on retaining Orthodox values, while the Neo-Eurasianist

Panarin considered the idea of an Orthodox-Turkic Islam synthesis.

Dugin's 'Fourth Political Theory' advocates a general idea of civilizational distinctiveness

and spirituality.

The Eurasian agenda for domestic politics and the economy generally reflects the Classical

Eurasianist Savitsky's idea of 'masterocracy'.

Masterocracy rejects the idea that good policy can be reduced to one or two metrics.

Instead, 'masters' need to exercise a benevolent stewardship over society and the

environment, not accountable to their subjects but nevertheless ideologically motivated to

promote the development of people in harmony with natural order.

Masterocracy therefore promotes top-down guidance over society: on the economy, Dugin translates

this into state control over strategic sectors – defence, natural resources, communications,

finance – to ensure that profit does not override civilizational values or unity.

On politics, he mirrors this by calling for an 'organic democracy' where, instead

of vote-counting, local elites rule and guide society with popular feedback.

Bound together by ideology, Eurasianism's ideal society blends strategically-directed

top-down government with strong local autonomy.

But this forms only the beginning of Eurasianism's historical task; the next objective is the

rollback of Western influence across the globe.

A unified Eurasia, in the Neo-Eurasianist Dugin's view, faces a world that is dominated

by Atlanticism in three ways.

Geographically, Atlanticism's control of both the Atlantic and Pacific rims allows

it to pressure all other coastal civilizations in an 'Anaconda Strategy'.

Institutionally, Atlantic dominance is cemented in a range of formal and informal structures

from NATO to the US reserve currency to its transnational companies.

Finally, there is informational dominance, exemplified in Atlanticism's use of its

influential mass media to spread its value discourse.

Eurasianism's operational response is asymmetric warfare.

Avoiding contests in sectors or against enemies with an unfavorable balance of power, Dugin

proposes redirecting competition into areas that are more favorable, such as natural or

energy resources, or else striking at the meta-dimensions of power like international

law and political decision-making.

Here Dugin particularly emphasizes the cyber realm's ability to bypass the formal institutions

of Atlanticist hegemony.

Asymmetric internet warfare undermines Atlanticist informational hegemony and allows Eurasianist

supporters to present civilizational and values alternatives to Atlanticism.

But on a strategic level, where should the rollback begin?

The first answer is: everywhere, in what Dugin calls a 'Coalition of the Dissatisfied'.

Eurasianism needs to make common cause with anti-Atlanticist movements regardless of ideology,

because even the most irrelevant or futile movement serves two purposes: firstly, it

presents an alternative to Atlanticism, and secondly, it draws Atlanticist resources away

from the key areas of competition.

Which brings us to the second answer, where Eurasia gradually replaces Atlanticist hegemony

with a new system of global multipolarity.

A unified Eurasia will already have bulwarks in Eastern Europe and the Middle East; now

the Anaconda's constriction has to be broken decisively via a strategic partnership with

India, which also grants the Eurasian bloc a 'central position' regulating interaction

between Europe, Asia and Africa.

Eurasia can then exploit the advantages of the central position to speed up the erosion

of Atlanticist power in Western Europe and East Asia, encouraging their return to civilizational

independence in a grand alliance linking Germany, Japan, India and Eurasia.

Penned back into its own environment, Atlanticism will resume its proper position as only one

of four power poles involved in global management: Western Europe, East Asia, the Atlantic Civilization,

and Eurasia.

This system is only sustainable with global economic and social reorganization.

Dugin argues that the previous model of geographic and economic integration, with Atlanticism

at the center and everybody else at the periphery, has to be replaced by a model of 'Vertical

Belts' where each 'Northern' civilization is more linked to its 'Southern' counterparts

rather than with each other.

The idea is presumably to hasten the civilizational development and integration of the 'global

South', resulting in an international system where all civilizations are strong and independent

enough to participate as equals – a reflection of Earth's natural order.

With this overview of Eurasianism's strategic logic, we now turn to a brief look of the

theory in practice.

Certainly aspects of Russian strategy, such as its emphasis on civilizational separateness

and sovereignty, special Russian values and the use of asymmetric and informational warfare,

are in line with Eurasianist thinking.

But does that mean Russia is now putting Eurasianist theory in practice?

Two things to note: firstly, Eurasianism is not necessarily popular within Russia, as

ethnic nationalists and the broader populace suspect that such a strategy would have Russia

send resources to and receive immigrants from the poorer Central Asian states.

Secondly, Eurasianist tropes are frequently used to justify non-Eurasianist ends.

Kazakhstan, for example, has been a consistent promoter of Eurasianist ideology, but its

emphasis has always been on Kazakh distinctiveness and sovereignty as a counter to Russian-led

integration.

This may also be the case for Putin's 'pragmatic Eurasianism', where Russia engages in Eurasian

integration but justifies it in liberal or even Atlanticist terms.

Dugin claims that this is deception, but it's possible to promote regional integration without

buying into Eurasianism.

An example of this is the Eurasian Economic Union, established in 2015 and so far involving

Armenia, Belarus, Kazakhstan, Kyrgyzstan and Russia.

Putin stressed that the EEU is not a tool for political unification: instead, by banding

together the EEU's members get to negotiate from a stronger position and thus get more

out of globalization – clearly not a Eurasianist move.

At the same time, however, the EEU – by taking down barriers, creating a single capital

and labor market and coordinating macroeconomic policy – clearly also encourages a Eurasian

economic unity whose development can be directed from a single strategic center.

Furthermore, despite all the talk about globalization, Putinist Eurasian integration tends to reject

Western influence – most notably denying Ukraine's 2013 proposal to be integrated

into both the EU and the Eurasian Customs Union, sparking off the Euromaidan protests.

All in all, while Russia has made Eurasian integration a foreign policy goal, this is

not necessarily the same thing as Eurasianism.

Putin's pragmatism and domestic constituency prevent him from associating with something

as explicitly pro-Central Asia and anti-Western as Eurasianism.

It is unlikely that the ideology will become formal state policy in the years to come,

if ever.

In conclusion, Eurasianism defines power not just politically but also in terms of civilizational

values.

These values reflect a distinct adaptation to their environment, which is why the universalism

promoted by Western hegemony has to be rejected.

To achieve this, Eurasianism proposes a united, ideologically mobilized civilization that

takes the lead in establishing a multipolar world.

It's probably safe to say that nobody who isn't already attracted to Eurasianism will

find its reasoning particularly convincing.

Eurasianism has been criticized as a theory that first assumes Eurasia exists, then analyzes

the world on that basis.

Reject its assumptions on geography, civilization and values, and the theory looks like mere

justification for Russian expansionism and authoritarianism.

Even then, Eurasianism is still worthy of analysis.

For starters, its declarations on civilizational uniqueness and universalism's corrosive

effects attract support, Russian or otherwise.

It also reminds Western strategymakers that the benefits of universal values are not self-evident

and can actually be perceived as harm, if not a mortal threat to society.

Recognizing this prevents strategic blunders like the EU's Eastern Partnership Program,

where its self-assured promotion of political and economic reforms in Eastern Europe discounted

Russia's reaction to what it saw as a perceived assault on its interests, catching the EU

unprepared and off-guard during the 2014 Ukrainian Crisis.

At the same time, Eurasianism also blinkers Russia's strategic perception.

By portraying Western values as incompatible yet uniquely aggressive, Russia loses the

chance to reflect on what makes them attractive and powerful.

The contest between Russia and the West also becomes eternal and there is no room for any

permanent compromise.

Eurasianists also discount the power of material strength, confident in overcoming it via ideological

mobilization or asymmetric warfare.

Unfortunately, reality seems to indicate otherwise.

Even the 'natural order' of Eurasian economic integration was reversed in 2015 and 2016

thanks to the impact of Western embargoes.

Ultimately, Eurasianism's rich intellectual diversity masks a theory that is short on

practical political experience.

But its ideal of a world filled with independent, distinct civilizations is an enticing one

to many, and it would be interesting to see if the world moves in that direction with

the continued relative decline of Atlantic power.

Thanks for watching the video, and please like and subscribe!

If you have any questions, I'll be happy to answer them in the comments section.

For more infomation >> The Strategy of Eurasianism - Duration: 26:08.

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Grimm Audio History and Mu1 digital player - Duration: 14:00.

A few weeks ago Grimm Audio organised the formal introduction of their MU1 digital music

source.

It does FM, streaming and play-back of your music.

I won't review the MU1, primarily because I have limited myself to review equipment

up to about 2,000 euros.

But I will tell you about the product and the people of Grimm Audio.

Grimm Audio was founded in 2004 by Eelco Grimm, Bruno Putzeys , Guido Tent and Peter van Willenswaard.

Bruno and Guido have worked for Philips while Eelco and Peter have a joint background at

ConTekst Publishers, the publishing company I started in 1989.

Peter already worked with me in the predecessor, Bureau ConTekst, that produced reviews and

other editorial productions for magazines in the Dutch and English language.

We covered mainly pro and consumer audio but also occasionally computer tech.

Dissatisfied with the influence advertisers had on editorial I started my own magazine

for the professional audio world, called Pro-Audio Magazine and Peter became the technical editor.

A few years later this magazine was renamed Pro Audio Video.

Eelco joined and after some years became the editor in chief.

Digital audio was still in its infancy so there was a lot to discover.

Already in the mid 80's I heard differences between digital connections and that fascinated

Peter heavily.

Quite frequently we were told that bits are bits and if we thought we heard a difference,

it was pure suggestion.

It would take quite some years before it became clear that this was caused by jitter.

If you search back Stereophiles from that period, you will find Peter reporting on our

findings with jitter since he was the Dutch correspondent for Stereophile then.

It was the time that we were invited to the Digital Information Exchange in London, we

reviewed well over a ton costing digital multitracks by Sony and Otari, professional and consumer

DAT recorders and digital mixing consoles.

I recall Eelco reviewing a digital mixing console, end 90's, that was Windows based

and that outputted undithered 20 bit audio.

The distributor and the manufacturer couldn't understand why that was a problem.

And believe me, that is quite a problem and will result in a rather harsh sound.

I also recall Peter reviewing one of the first products by Daniel Weiss, the Penguin digital

processing unit.

That showed us how /good/ digital processing could be.

It were fascinating times and we learned a lot about digital audio.

Peter left my company in 1993 to join the Dutch distributor of Audio Note, where he

must have met Guido Tent.

When he left there, it was to start his own company Audiomagic that develops, builds and

repairs high end tube based audio equipment for consumers and manufacturers.

Eelco quitted his job at ConTekst Publishers in 2000.

He already started his own location recording company in 1997 called Fairy Tapes and became

a part time professor at the University of the Arts Utrecht, Arts and Technics department,

something he still does.

In 2008 he also became PLAUD Committee member for the European Broadcasting Union.

This committee developed standards for equal loudness in TV and radio.

This standard is adhered to b many broadcaster - at least on this side of the pond.

In the mean time Guido left the Audio Note distributor and had worked at Philips for

nine years before he started Tentlabs, famous for the extremely low jitter Tentlabs Clock

but Tentlabs also produces hifi-equipment.

Bruno in the mean time had developed the well known class-D module for Philips.

These modules nowadays are sold under the Hypex brand.

In 2004 all this expertise merged together in Grimm Audio.

Their first product was the 1-bit AD1 analog to digital converter which still is popular

amongst recording studios that record in DSD, like Channel Classics.

As a spin-off the CC1 master clock was developed and the famous Wisseloord Studios in Hilversum

The Netherlands wired their studios using the Grimm Audio TPR cable.

They introduced active speakers that were built along unique thoughts.

Take for instance the half rounded tubes used as stand and bottom of the speakers.

This rounding is chosen to have specific positive influence on the acoustic behaviour.

Also the limited physical depth is remarkable and beneficiary in small control rooms like

the recording control room at the Amsterdam Concertgebouw where a full 5.1 monitoring

system is installed.

The founders all kept other work along the side, Eelco as professor, Bruno as developer

for Hypex, Guido for his company Tentlabs and Peter for his company Audiomagic.

In 2012 Bruno left to do further develop the Hypex modules for the Mola Mola company and

after two years switched to Kii Audio.

A year later Peter in his own words "attempted to retire".

He formally left the company but still spends one day a week at Grimm Audio and also does

work he likes in his own company.

Currently three versions of the Grimm Audio speaker are available, all having the same

cabinet but different drivers and matching electronics.

Also two types of subwoofers were introduced.

They integrate with the speakers both mechanically, acoustically and electronically.

One is a conventional type and one uses motional feedback to further reduce distortion by 30

dB's.

Both are positioned woofer-up between the legs of the speaker and when mounted the DSP

in the speakera are set to fully integrate the sub.

January 31st 2019 Grimm Audio held the formal introduction of their digital front-end at

the Van Abbemuseum, the contemporary arts museum of Eindhoven, The Netherlands.

Art is close at the hearts of Grimm Audio.

The presentation started with the unveiling of the very good looking unit by Guido and

Eelco.

Guido on the left and Eelco on the right.

It was followed up by short reports by the people involved in the development of the

MU1. [video quote Peter over components] followed up with a tableau of all Grimm Audio developers

on stage.

After a Q&A session it was time for music.

Live music that is.

Cellist Maya Fridman and harpist Majsa Koperberg played individually and jointly six pieces.

Maya started of with the composition The Song of Songs for cello and electronics by Karen

Tanaka.

The electronics were reproduced over the MU1 front-end and the LS1 speakers.

I know this piece since it has been released on her Red Velvet CD under the TRPTK label.

It is available on Tidal and Qobuz too.

That track was recorded live in de same way it was played back at the MU1 introduction

and it is shocking to hear how well the reproduced electronic music and the live cello blended

in together.

Maya is a fascinating cellist that not only does classical music but also jazz and even

rock music, as you might gather from Quintessence, composed by Oene van Geel.

It also uses the Grimm Audio setup for the electronic music.

Majsa also played lovely.

By the way, the dresses the ladies wore were originally designed for promotion shoots by

Brendon Heinst for the Grimm Audio brand…..

The MU1 is a very comprehensive front-end for the Grimm Audio speakers but can also

be connected to the digital inputs of an already existing system.

So it only has digital outputs, six in total that - in the near future - can be used for

surround when you use five Grimm speakers plus subs, a six channel D/A converter or

three stereo D/A converters.

On the input side there are AES/EBU, SPDIF and optical inputs so you can connect for

instance the digital output of the tv, a cd-player with digital output, Chromecast Audio, Apple

TV or a game console.

Or even a bluetooth receiver for your son that mainly appreciate the loudness your stereo

can produce.

Internally there is an FM receiver and a Linux based music player that by default has Roon

installed although an MPD based player can be installed on request.

It can work with Tidal, Qobuz, Primephonic an Spottify Connect.

Music can be stored on the internal SSD, an external USB drive and a NAS.

So far no more than any Linux computer with FM tuner card can do.

But in the case of the MU1 there is a proprietary FPGA sound card with extremely precise clocks

and its own PCIe drivers.

The code on the sound card is fully optimised for high quality audio playback.

Grimm Audio claims unparalleled upsampling algorithms and audio format conversion.

Since this is not a review, I won't comment on those claims other than that knowing the

guys I expect it to be no less less than very good.

This is an odd video in the sense that I never do company profiles.

But in the past I kept a distance to Grimm Audio to avoid even the suggestion of partiality.

Almost two decades later I did realise that I have grossly overdone that and that my ex

colleagues deserved a fairer treatment.

I hope this video will give you a bit more insight in the background of my ex-colleagues

and the other Grimm Audio founders.

You are what you live and they have lived audio to the full, bringing them not only

a lot of experience but also knowledge.

Add that to the love for music.

I wholeheartedly congratulate the Grimm Audio company for achieving the goal they reached

out for : extremely good sound quality.

I personally love the simple to operate setup.

I would urge you to go and listen for yourself.

Next week you can expect again a regular video.

So if you don't want to miss that, make sure you are subscribed to this channel or

follow me on the social media so you know when new videos are released.

If you liked this video, give it a thumbs up.

Many thanks to all that support this channel financially, it keeps me independent and thus

trustworthy.

If you also feel like supporting my work, the links are in the comments below this video

on Youtube.

I am Hans Beekhuyzen, thank you for watching and see you in the next show or on theHBproject.com.

And whatever you do, enjoy the music.

For more infomation >> Grimm Audio History and Mu1 digital player - Duration: 14:00.

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¡Adamari y Rashel nos comparte sus secretos de belleza! | Un Nuevo Día | Telemundo - Duration: 4:27.

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World's RICHEST People | Last 20 Years ● Ranking History 2000-2019 - Duration: 4:03.

For more infomation >> World's RICHEST People | Last 20 Years ● Ranking History 2000-2019 - Duration: 4:03.

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Michael Laufer: Open-Source DIY Pharmaceutical Grade Medicines For All - Duration: 6:47.

LBW: If you could give some examples of like medicines that you have produced using this, I think it's your microlab medicines

that you've worked on that have been really effective that that people can have access to now.

MICHAEL LAUFER: So the things that we're currently working on we're trying to find the medicines that sort of need the most attention with

things that have the greatest impact.

and to which people seem to be blocked from access most often the

Four five main ones that we've been focusing on.

are

sovaldi which I mentioned before

there was daraprim which is the

anti-parasitic

drug that is works to cure toxoplasmosis there was the big hoopla over from Turing Pharmaceuticals and Martin Shkreli

There is Mifepristone and Misoprostal which are the abortifacient drugs again a very old establish technology, but again one

that people don't have a lot of access to in a lot of places.

And then on top of that

there's naloxone

which is again, another very well-established very very safe technology that

interrupts opiate overdose and reverses it.

But again is very hard to get.

Especially for the people who need it.

and additionally we're working on trying to proliferate some of the HIV antiretrovirals that are more effective but harder

to get

So.

LBW. Okay. Yeah, those are some obviously things that people are like in immediate need of and and if you were to compare say the

price of an EpiPen

to the EpiPencil or ay any other drugs that you just mentioned just now, what would be the variable that

like the difference between these prices?

MICHAEL LAUFER: Yes, so the EpiPen/EpiPecil comparison is a good one

because it's very concrete so

a pair of EpiPens

go for about $600 US.

And they have a shelf life of 18 months.

The EpiPencil you can build from scratch for just over $30.

But you can reload it for $3.

Now it's shelf life is significantly shorter at 3 months, but

reloading something for $3 every 3 months rather than reloading something for $300 of 18 months is a significant difference

still an order of magnitude larger and it's it's it's amazing because that particular project we didn't even plan on

doing it. It was blowing up with [?].

People were contacting us through the web page and say why aren't you doing something about the EpiPen why aren't you doing something about the EpiPencil?

We're trying to do chemistry, we don't really do medical hardware.

It's kind of not our thing and people said it should be.

Because this is what you stand for. You should be doing it.

And so there was a discussion.

And we all sort of threw it around and said, well, I know we're in the middle of a lot of other things but she's maybe put that on hold and

work on this and everybody said yes, let's let's just do this so we

went looking for

What are the gap was and we looked into the chemistry of epinephrine and we realize that's not the gap at all. You can get

epinephrine in any any pharmacy anywhere.

If you have a prescription.

And it cost you a dollar.

Roughly

And so it was suddenly this moment of scratching our heads saying so why is this damn thing so expensive? That's so weird, and

it was just that they have a corner on the market.

and the

intellectual property of owning the patents to that particular auto-injector.

And so we said that's silly

let's just find another auto-injector and and hijacked the technology and load it with the something else.

The thing that's very odd is that

despite what we expected there aren't many auto-injectors out there. There is a there's a glucagen pain for diabetics,

but that doesn't use a syringe that uses a little

sack that holds the glucagen

And then the only other ones that we found were antidotes

to

certain chemical warfare agents that the U.S. and the Israeli military use and so those are of course

are not

accessible either and so we were poking around saying there has go to be a way to do this.

There's one company that sells a reloadable auto-injector that's designed for needle phobic diabetics.

And he said I look great let's just use this.

The problem then is of course

Diabetic syringes are very very thin

and have a very small needle and this isn't a terrible problem because the amount of epinephrine that you need you inject is

very small

it's roughly a third

of a milliliter, 3/10ths

but it's an intramuscular so you need a fairly fat needle and so most of our

sort of researched time was spent trying to find a way to mate a very large needle with a very small syringe and we

finally found there's a very simple way to

get them to play nice together and then you go out and

buy some needles you buy some syringes and and everything fits together.

LBW: Wow. Yeah, you just put that together and I'm sure that people are very grateful.

that you guys put that together.

MICHAEL LAUFER: I hope so. I've heard sort of peripheral stories people using them.

So it's nice to hear that it's out there.

That people are doing well.

For more infomation >> Michael Laufer: Open-Source DIY Pharmaceutical Grade Medicines For All - Duration: 6:47.

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Top 5 Best Android TV Apps 2019 - Must Try! - Duration: 2:18.

Top 5 Best Android TV Apps 2019

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Chelsea press conference live: Gianfranco Zola previews Man United clash - Duration: 3:19.

Video LoadingVideo UnavailableClick to playTap to playThe video will start in 8CancelPlay now Hello and welcome to Cobham where Chelsea assistant head coach Gianfranco Zola is set to speak to the press ahead of their FA Cup fifth round clash with Manchester United on Monday night

 The Blues are coming off the back of a 2-1 win at Malmo last night, but still with the 6-0 hammering by Manchester City last weekend fresh in their memories

 The clash on Monday night is the beginning of a massive six days for the Blues as they have three matches in that time

After United, they host Malmo in the Europa League last 32 second leg, before the Carabao Cup final at Wembley against City

   United suffered their first defeat under Ole Gunnar Solskjaer in midweek when they were beaten by PSG in the Champions League and they will be keen to bounce back

 Meanwhile, we'll be getting the latest injury news on Ruben Loftus-Cheek and whether Marcos Alonso might feature

 football.london's Chelsea correspondent Oliver Harbord is live from Cobham to hear what Zola has to say

 Follow all the updates below.    Keep up to date with the latest news, features and exclusives from football

london via the free football.london app for iPhone and Android.  Available to download from the App Store and Google Play

Key EventsZola is here15:0415:17That's it Zola is done for now.15:17Strongest team possible?15:16Injury news15:15Hudson-Odoi, does he feel wanted in the group?15:13Higuain15:12No replays in fifth round, an advantage?15:11How do you see the game pan out?15:10How have United changed?15:09Ole impact at United?15:08Turnaround?15:07Pivotal time for Chelsea?15:05Looking forward to playing United?15:04KEY EVENTZola is here15:02United injury blow There is something of a boost for Chelsea ahead of the Man United match

Check out their injury news right here.14:39In place Oliver Harbord has hopped off a plane from Malmo to head to Cobham to bring you all the news from Zola

14:36Hello and welcome We're live from Cobham where Gianfranco Zola is set to speak to the press ahead of Chelsea's FA Cup match with Manchester United

For more infomation >> Chelsea press conference live: Gianfranco Zola previews Man United clash - Duration: 3:19.

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Exfolia tu cuero cabelludo con estos métodos caseros | Un Nuevo Día | Telemundo - Duration: 5:14.

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СТИЛЬНЫЕ АВТОРСКИЕ КОЖАНЫЕ БРЮКИ. Как красиво изменять размер и фасон кожаных брюк вставками - Duration: 10:35.

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Where is Chicky Cartoon 2018 | Funny Cartoon For Kids In English | Episode 39 - Duration: 0:56.

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