HARVARD RESEARCHERS BELIEVE THAT THEY CAN REVERSE DNA AGING.
WELL AT LEAST THEY PROVEN THAT THEY CAN REVERSE DNA AGING
IN MY SENSING THEY WILL BE TESTING THIS METHOD ON
HUMANS AND IT IS A PRETTY BIG DEAL.
THEY FOCUSED ON AN INTRIGUING COMPOUND WITH ANTIAGING
PROPERTIES CALLED NAD+.
IT'S BEEN KNOWN THAT YOUNGER MICE HAD MORE OF IT THAN
OLDER MICE AND BACK IN 2013, THE RESEARCHERS FOUND THAT WHEN
THEY BOOSTED THE NAD+ LEVELS IN OLDER MICE THEY LOOKED,
BIOLOGICALLY, LIKE MUCH YOUNGER ANIMALS.
BANANAS.
THEY COULDN'T EVEN DIFFERENTIATE BETWEEN THE
OLDER MICE IN THE YOUNGER MICE AFTER THEY STARTED GIVING
THE OLDER MICE THIS COMPOUND.
SINCLAIR, THAT'S ACTUALLY DOCTOR DAVID SINCLAIR FROM
HARVARD, PUT DROPS OF NAD+ INTO THE WATER OF A GROUP
OF MICE AND WITHIN A COUPLE OF HOURS, THEIR NAD+ LEVELS
STARTED TO RISE THAT WITHIN THE FIRST WEEK, THE SCIENTISTS SAW
OBVIOUS AGE REVERSAL IN MUSCLE AND IMPROVEMENTS IN DNA REPAIR.
THAT'S IT, WEíRE DONE.
THIS IS THE MOST IMPORTANT STORY THAT WE HAVE EVER COVERED.
NOTHING ELSE MATTERS AT THE
I AGREE WITH HER.
THIS IS FREAKING PHENOMENAL AND I'M SUPER EXCITED THAT
I WANT TO GET MY HANDS ON NAD+ IMMEDIATELY.
I'M LOOKING AT CENK UYGUR'S NOTES AND THEYíRE
HIGHLIGHTED THROUGH AND THROUGH.
THE ENTIRE ARTICLE IS HIGHLIGHTED THROUGH AND
THROUGH.
YOU DIDN'T HAVE THIS LEVEL OF DETAIL -
I DONíT KNOW IF YOU CAN SEE ALL THE HIGHLIGHTS.
I GOT EXCITED I'M NOT MESSING AROUND WITH THAT.
YOU HAVE TO STOP EATING NOW IF YOU WANT TO REMAIN
HEALTHY REGARDLESS OF HOW YOUNG YOU BUT.
NOT NECESSARILY MAN, AND THEN HAD PLEASANT EVERYTHING IS
GOING TO BE OKAY TO LET ME QUOTE THE GOT THE DOCTOR AGAIN.
WE CAN'T TELL THE DIFFERENCE BETWEEN TISSUES FROM AN OLD
MOUSE THAT IS TWO YEARS OLD VERSUS A YOUNG MOUTH THAT IS
3 TO 4 MONTHS OLD.
GOOD NIGHT, IRENE.
OR NO GOOD NIGHTS.
WEíRE GOING TO GET YOUNGER AND YOUNGER
AND YOUNGER.
HIT ME WITH NAD+.
THE BEST PART IS YOU DON'T HAVE TO DO ANYTHING INVASIVE.
YOU JUST HAVE TO CONSUME IT.
BUT, IF THEY DID A TEST ON HUMANS WITH WHICH THEY PLAN
ON DOING.
THEY'RE GOING TO DO THE FIRST TEST ON 25 HUMANS TO SEE WHETHER
OR NOT IT HAS THE SAME IMPACT ON THEM LIKE IT HAS ON THE
MICE, BUT THE MICE JUST DRINK THAT SHIT UP.
YOU KNOW?
THEY DIDNíT HAVE TO DO ANYTHING CRAZY.
NO IMPLANTS OR INJECTING ANYTHING.
THEY INGESTED IT.
WE WOULD JUST HAVE TO INGEST IT.
IT IS THE MAGIC PILL.
IT'S ALSO THE COMPOUND FOUND IN MICRO-DOSES AND
BROCCOLI, AVOCADO, CUCUMBERS, THINGS THAT I EAT A LOT
ACTUALLY, BUT WHAT I WAS GOING TO SAY THAT'S
IT'S NOT WORKING ON YOU.
WELL, DO YOU HEAR THAT?
HERE'S WHAT I'M GOING TO
SAY ñ IS NO ONE TERRIFIED BY THIS?
THIS IS EVERY PLOT POINT TO EVERY ZOMBIE MOVIE EVER.
THIS IS EXACTLY HOW ZOMBIE MOVIE START.
THIS IS HOW YOU START.
BLACK HELICOPTERS, ZOMBIES, I'M
GLAD THAT THEY'RE DOING THE METRO BIOTECH IS IN BOSTON
SO AT LEAST WILL BE CONTAINED IN THE AREA.
WHAT MAKES YOU THINK IT WILL BE CONTAINED?
REMEMBER DEATH BECOMES HER?
25 PEOPLE ARE GOING TO TURN INTO ZOMBIES.
ARE GOING TO BE MISSING.
BUT LUCKILY BECAUSE IT'S IN THE BOSTON AREA THEY WILL
HANDLE IT QUICKLY BECAUSE EVERYONE KNOWS BOSTONIANS
ARE VERY AGGRESSIVE ESPECIALLY AROUND FOOTBALL SEASON.
I JUST GENERALIZED.
WEíLL GET BACK TO THE STORY.
THE
WAY WE AGE IS DNA COPIES ITSELF AND SOMETIMES WHEN IT COPIES
ITSELF IT'LL COPY A NOT SO PERFECT VERSION AND THAT IS
WHAT KIND OF LEADS TO AGING.
THAT IS AN OVERLY SIMPLISTIC WAY OF DESCRIBING AND
ESSENTIALLY WHAT HAPPENS IS YOUR BODY NEEDS THESE DNA REPAIR
COMPOUNDS IN ORDER TO REPAIR ITSELF IN A MORE EFFECTIVE
WAY, AND A BETTER WAY, AND A MORE PERFECT WAY I GUESS.
THAT IS WHAT PREVENTS AGING.
THAT IS WHAT THIS IS, THEN ADD PLUS IS A DNA REPAIR COMPOUND.
WITH HUMANS, THE REPAIR COMPOUND IS CONSUMMATE A LITTLE DIFFERENT
THAT I CAN'T PRONOUNCE IT, BUT THE SHORT VERSION IS MNM.
THE NATURALLY OCCURRING COMPOUND FOUND IN SMALL AMOUNTS
IN FOODS LIKE BROCCOLI, CUCUMBER, AVOCADO, EDAMAME.
I JUST WANT
THE RECORD I'M A BIG FAN OF AVOCADO TOAST.
I EAT A LOT OF
IT.
I FEEL VINDICATED ABOUT THAT.
CAN I JUST SAY ONE THING.
CAN Y'ALL CHECK TO SEE IF
Y'ALL CAN CURE THE RATS FROM CANCER?
WHY ARE WE SO
PREOCCUPIED WITH YOUTH IN AMERICA?
YOU CAN WALK AROUND WITH AN OLD SOUL.
IT DOESN'T MATTER IF YOUR FACE DOESN'T MOVE.
IT'S OKAY
TO GET OLDER.
WHY ARE WE SO PREOCCUPIED WITH NOT GETTING OLDER?
IT'S OKAY.
SO THAT'S A LARRY KING.
IT'S SO MUCH PRESSURE ON WOMEN ALL THE TIME WITH THIS.
STOP IT.
WE CAN BE INVESTING THIS TIME INTO SOMETHING ELSE.
IT'S NOT JUST ABOUT LOOKS, WHICH I WILL ADMIT, THAT'S
THE PART OF IT THAT I CARE ABOUT THE MOST, BUT IT'S NOT JUST
ABOUT THAT BECAUSE IT HELPS REBUILD HEALTHY TISSUE.
ALSO, YOU BROUGHT UP CANCER AND I'M GLAD THAT YOU DID BECAUSE
THIS COULD HAVE HUGE BENEFITS OF FOUR CANCER PATIENTS.
APPARENTLY, SCIENTISTS HAVE HARNESS THIS TO TARGET CANCER
CELLS, CANCER DRUG CALLED PAR PA INHIBITORS WHICH ARE PRESCRIBED
FOR BREAST CANCER INTERFERE WITH PAR P'S ABILITY TO REPAIR DNA IN
THE TUMOR WHICH ULTIMATELY LEADS TO THEIR DEMISE BUT NOW
PEOPLE WHO TAKE THE DRUG RESPOND WELL TO WAY AND MANIPULATE
THAT PLUS LEVELS MIGHT BE ONE WAY TO ENHANCE THE RESPONSE.
IT COULD HELP CANCER PATIENTS AS WELL.
LET ME TRY TO EXPLAIN, AGAIN ALL OF THIS IS A LITTLE
OVERSIMPLISTIC.
NOT PLUS, WHEN THEIR LEVELS ARE HIGHER THAN PAR P1 IS ACTIVATED
AND CAN REPAIR THE DNA.
IN THE CASE OF CANCER, YOU DON'T WANT TO REPAIR THE DNA OF
THE CANCER CELLS SO THEY ACTUALLY LOWER THE PART AND
THAT WINDS UP KILLING THE CANCER.
IN THE CASE OF REVIVING YOUR YOUTH, YOU WANT THE PART TO BE
HIGH ANYONE THAT PLUS LEVELS TO BE, BECAUSE WHEN THAT PLUS
LEVELS ARE HIGH THAN PART ONE IS ACTIVATED AND THEN YOUR DNA
HEELS AND YOU BECOME YOUNGER.
THE BOTTOM LINE IS WE'RE NOT GOING TO DIE.
I
AM NOT PLAYING.
LET ME GET REAL, I KNOW IT SOUNDS A LITTLE LIKE THE ZOMBIE
THING THAT HOSPICE TALKING ABOUT, AND I AM NOT SAYING THEY
IF YOU HAVE IN A CAR ACCIDENT, BEGIN A CAR ACCIDENT YOUR DEAD.
OF COURSE.
THIS DOESN'T MAGICALLY UNDEAD YOU.
YOU ARE NICELY GOING TO HAVE ZOMBIES.
THIS IS HOWEVER A TIME, AND EVERY SINGLE MOVIE
LET ME TALK ABOUT HOW IT'S GOING TO BE REAL THOUGH.
WE ARE ON THE EDGE OF SCIENTIFIC BREAKTHROUGHS THAT ARE
GOING TO CHANGE THE ENTIRE WORLD.
THE NUMBER ONE PROBLEM IS, I TALK ABOUT ALL THE TIME ON
THE SHOW WHETHER IT'S POLITICS OR ANYTHING ELSE'S PEOPLE
CANNOT SEE OUTSIDE OF THEIR OWN PERSPECTIVE.
IN OUR LIFETIMES, WE'VE EVER SEEN IS THIS.
YOU AGE, YOU GET OLDER, YOU CANíT MANIPULATE YOUR GENES, ETC.
WE ARE ABOUT TO MANIPULATE THE GENES.
WE ARE ABOUT TO MANIPULATE THE DNA.
ITíS GOING TO AFFECT
PEOPLE THAT ARE ALIVE.
ITíS GOING TO AFFECT BABIES EVEN
MORE BECAUSE WE CAN CHANGE THE DNA WITHIN THE WOMB.
THAT IS NOW BORDERLINE EASY.
I'VE BEEN TALKING ABOUT THIS FOR LONG TIME AND HE THINK I AM
PLAYING OR EXAGGERATING.
I AM NOT THAT THEY ARE GOING TO BE SUPER BABIES.
THEY'RE GOING TO HAVE SLIGHTLY DIFFERENT GENES THAN US.
THEY COULD BE STRONGER, IT'S POSSIBLE THEY COULD BE SMARTER.
NOW YOU ARE TALKING ABOUT REAL SCIENCE-FICTION MOVIES BUT
ISN'T FICTION ANYMORE.
AND NOW, SCIENCE HAS ADVANCED SO MUCH THAT YOU MIGHT BE ABLE
TO MANIPULATE GENES OF A PERSON WHO IS ALREADY ALIVE TO
CURE THEM OF THINGS INCLUDING GROWING BACK LIMBS.
WE CAN'T UNDERSTAND IT.
ITíS A DIFFERENT PERSPECTIVE.
WE THINK THAT CAN'T BE TRUE, RIGHT?
SO WHEN WE LOOK AT THIS STUFF AND YOU THINK KNOW, YOU ARE
EXAGGERATING.
IT CAN'T REALLY MAKE YOU YOUNGER.
IT ALREADY MADE THE MICE YOUNGER.
IT ALREADY HAPPENED AND
THEYíRE TESTING IN HUMANS.
NOW 48 YEARS FROM NOW, NOT 88
YEARS FROM NOW, NOT A BRAVE NEW WORLD, TODAY.
IT DOESN'T MEAN THAT IT IS GOING TO HAPPEN IN 18
MONTHS AND ALL OF A SUDDEN WE'RE ALL IMMORTAL.
I ALSO WANT TO BRING DOWN YOUR EXPECTATIONS.
OF COURSE THIS IS DANGEROUS AND IMPORTANT STUFF.
THEY'RE GOING TO DO A TON OF TESTING BEFORE THEY ARE
LIKE HEY, EVERYBODY NOT PAUSE FOR EVERYONE.
YES WE ARE OVERSIMPLIFYING TO ALL THE THINGS ARE TRUE.
BUT IF NOT FOR OUR GENERATION, DEFINITELY FOR KIDS
GENERATION IS DEFINITELY GOING TO BE COMPLETELY DIFFERENT.
ONCE YOU START MESSING AROUND WITH THE GENES, ALL BETS
ARE OFF.
FOR THE GOOD AND PROBABLY ALSO FOR THE BAD.
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