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Health Network, For Public Health
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The disease is engraved by each other
Genetic disorders are transmitted from generation to generation. If you only get the gene from the parent, you will be called the disease carrier.
Similarly, some infections sometimes give rise to resistance to other diseases.
1. Sickle cell disease and malaria.
People who carry the sickle cell gene have been shown to be more resistant to malaria. Sickle cell disease is a genetic disease in which red blood cells become deformed, becoming sickle-shaped and more prone to clumping together.
According to the CDC, 60% of people with sickle cell disease survive malaria.
This means that, in areas with high prevalence of malaria, Central and South America, Africa, Asia, and India and the Pacific, crescent bridge
Sickle cell disease prevents malaria, thanks to a hemoglobin component, haem. Low haem levels stimulate haem oxengase-1, also haem haemolysis.
This allows carbon monoxide to become more apparent in the blood
Because haem oxengase-1 releases carbon monoxide, plays an important role in preventing malaria.
A group of scientists tested on mice, and observed these results.
Sickle cell disease.
2. Hand-Sachs Disease and Tuberculosis.
People with Tay-Sachs disease show that the Tay-Sachs disease gene protects against tuberculosis Mycobacteria tuberculosis.
Tay-Sachs disease destroys neurons in the brain and spinal cord, more common in Ashkenazi Jews, probably due to isolated living conditions and lack of immigration.
There was a correlation between Tay-Sachs and tuberculosis in this particular population.
However, people who carry the Tay-Sachs gene, produce a certain subtype of the hexosamindinase enzyme.
This subtype is closely related to preventing TB, as it destroys Mycobacteria, and causes other bacteria on the cell surface to become less active.
Thus, despite the increased incidence of tuberculosis in Ashkenazi Jews, the number of deaths due to the disease is lower.
Beef and beanpox.
Beanpox, a skin infection caused by the virus, is basically a mildpox. Although cowpox is not necessarily pleasant to suffer
The human body will prevent the progression of infection, after a certain period of time, so the infection is not lethal.
Bovine herpes zoster can prevent smallpox, as both of them are essentially the same form of infection.
By being exposed to cow's beef infection, the immune system can develop immunity to the virus.
When the deadlier version of the infection appears, the immune system will easily prevent serious harm.
Edward Jenner used cowpea to produce smallpox vaccines in the late 1700s.
4. Muscular weakness and rabies.
There is a correlation, between patients with myasthenia and rabies prevention.
Myasthenia gravis, a muscle disease, in which the motor muscles become tired and weakened.
Caused by faulty connections between the nervous system and the musculature. Rabies infects the nervous system
The most common is through skeletal muscle muscles, possibly because rabies is usually transmitted through animal bites.
Because rabies is usually injected into the muscular system through the bite, people with myasthenia gravis are less susceptible to rabies, because their muscular and nervous connections are defective.
Rabies will be very difficult to harm the nervous system, when it was not able to penetrate it from the start.
Although muscles are not the only gateway, rabies infiltrates the central nervous system
But this is an important gateway to the peripheral nervous system.
This can prevent infection or delay it, until the patient can seek medical attention.
5. Niemann-Pick disease and Ebola.
Niemann-Pick is a disease in which, cholesterol builds up abnormally in lysosomes.
Cholesterol accumulates due to lack of a specific protein called NPC1
It is the task of transporting cholesterol away from the lysosome.
It has been demonstrated that NPC1 protein is involved in Ebola infection.
Ebola virus has been reported to be inferior, in the fibroblasts of patients with Niemann-Pick disease
while it works better at fibroblasts where NPC1 is plentiful.
Basically, Ebola virus can not effectively infect people with Niemann-Pick disease
Without the presence of NPC1 virus will be extremely difficult to operate.
Doctors:Camtu, Listverse.
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Wish you always healthy.
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